منابع مشابه
Glutamate receptor pores.
Glutamate receptors are ligand-gated ion channels that mediate fast excitatory synaptic transmission throughout the central nervous system. Functional receptors are homo- or heteromeric tetramers with each subunit contributing a re-entrant pore loop that dips into the membrane from the cytoplasmic side. The pore loops form a narrow constriction near their apex with a wide vestibule toward the c...
متن کاملOpening closed pores
JCB • VOLUME 167 • NUMBER 6 • 2004 994 Opening closed pores closed mitosis may be less closed than was thought, based on results from Colin De Souza, Stephen Osmani, and colleagues (The Ohio State University, Columbus, OH). The authors find that a fungus opens nuclear pores during mitosis to permit diffusion into and out of the nucleus. Simple organisms may thus be viable model systems for the ...
متن کاملPores in the Wall
Address correspondence to Shoichiro Tsukita, M.D., Ph.D., Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Tel.: 81-75-753-4372. Fax: 81-75-753-4660. E-mail:htsukita @mfour.med.kyoto-u.ac.jp 1 Abbreviations used in this paper: CPE, Clostridium perfringens enterotoxin; TJ, tight junction. In vertebrates, tight junctions (TJs) 1 play a central ro...
متن کاملPores of Kohn.
The history of the investigations into interalveolar communications (pores of Kohn) shows that the question whether they exist and, if so, their nature has for approximately a century been contentious. The present electron microscopic study of the lungs of mice demonstrates that alveolar pores are normal structures, with edges composed of intact alveolar wall. A number of planes are demonstrate...
متن کاملOctagonal Nuclear Pores
Negative staining of isolated nuclear envelopes by phosphotungstate shows that the nuclear pores are octagonal rather than circular. Pores of the same shape and approximately the same width, 663 +/- 5 A, were demonstrated in the newt, Triturus, the frog, Rana, and the starfish, Henricia. The outer and inner diameters of the annulus associated with each pore are respectively greater and less tha...
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ژورنال
عنوان ژورنال: Science
سال: 2010
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.328.5984.1329-c